I only mentioned 16" wide because it's what I have (T39). Comparing the min/max widths for 10 and 12 inch drivers, it seems 16" would be roughly appropriate for an eight... at least for a test just to see what happens. I wouldn't have to build anything except an adapter ring. However, the cab's at my dads house 350 miles away. So, it's not like I can give it a go in the morning. I'll grab it next time I'm down there.
The Tuba or Titan question... always some great opinions come out of that conversation and all of them seem valid. It seems to me, we have 3-4 things going on in considering the MCM for big boy duty;
Cost, size, weight, and curiosity. Pretty much the same as usual, just different
For me it's mostly curiosity. I love small drivers doing big things.
For size and weight, the argument could be made that the 3010LF would be a strong avenue to pursue.
Size and cost is where it seems your interest resides. Which, if you go the route of putting two drivers in a cab, it starts to diminish the size benefit. Although, it does offer in-box series wiring for an 8ohm cab.
I have pretty much come to the conclusion for myself that any indoor only system is Tuba territory and a system that will see any outdoor duty is automatically Titan territory... unless I'm able and willing to potentially double the cab and amplifier count. If I were to build a cab to test the MCM driver, I'm pretty sure I'd choose a Titan in favor of it's overall increased sensitivity. Especially since I'd be interested in maximizing the available output from a small driver. But, that's not to say that I'm not thoroughly curious how well it would perform in every cab design. I completely am. It just feels like the Titan is the right place to start.
On the other hand, since you already have 4 T45's, it might make sense to make a T45 in a size that could take a 12" driver so you could make use of the cab if the test didn't pan out to be a viable option in the end.
Neither is clearly the hands down way to go. Flip a coin?
Do you have casters on your T45's? If not, you may want to add some. They should wheel around effortlessly. Maybe put some 3012LF's in them to help with the weight a little?